适应症
用于口服混悬液和头孢克肟胶囊的头孢克肟适用于治疗由易感化脓性链球菌分离株引起的6个月或以上的咽炎和扁桃体炎的成人和儿科患者。（注意：青霉素是治疗化脓性链球菌感染的首选药物。用于口服混悬液的头孢克肟和头孢克肟胶囊通常可有效根除鼻咽部的化脓性链球菌;然而，尚无确定头孢克肟口服混悬液和头孢克肟胶囊在随后预防风湿热方面的疗效的数据。用于口服混悬液和头孢克肟胶囊的头孢克肟适用于治疗由淋病奈瑟菌易感分离株（青霉素酶和非产青霉素酶分离株）引起的无并发症淋病（宫颈/尿道）的成人和儿科患者。

用法用量
在开始头孢克肟治疗之前，应仔细询问以确定患者既往是否对头孢菌素、青霉素或其他药物有超敏反应。如果将本品用于青霉素敏感患者，应谨慎使用，因为β-内酰胺类抗菌药物之间的交叉超敏反应已被明确记录，并且可能发生在多达10%的有青霉素过敏史的患者中。如果对头孢克肟发生过敏反应，请停药。在没有确诊或强烈怀疑细菌感染的情况下开具头孢克肟不太可能为患者带来益处，并增加耐药细菌发展的风险。

不良反应
在美国片剂制剂试验中最常见的不良反应是胃肠道事件，30%的成年患者报告了每日两次或每日一次的方案。在美国临床试验中，百分之五（5%）的患者因药物相关不良反应而停止治疗。个体不良反应包括腹泻16%，稀便或大便频繁6%，腹痛3%，恶心7%，消化不良3%，肠胃气胀4%。接受悬浮液的儿科患者胃肠道不良反应（包括腹泻和稀便）的发生率与接受片剂的成年患者的发生率相当。过敏性/类过敏反应（包括休克和死亡）、皮疹、荨麻疹、药物发热、瘙痒、血管性水肿和面部水肿。多形性红斑、史蒂文斯-约翰逊综合征和血清病样反应已有报道。过敏反应、二重感染、肾功能不全、中毒性肾病、肝功能障碍包括胆汁淤积、再生障碍性贫血、溶血性贫血、出血和结肠炎。生殖器瘙痒，阴道炎，念珠菌病，中毒性表皮坏死松解症。

Counsel patients that antibacterial drugs, including cefixime, should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When cefixime is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may: (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by cefixime for oral suspension or other antibacterial drugs in the future.Advise patients that diarrhea is a common problem caused by antibacterial drugs which usually ends when the antibacterial drug is discontinued. Sometimes after starting treatment with antibacterial drugs, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibacterial drug. If this occurs, patients should contact their physician as soon as possible.