药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201921323100913.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文Reglan处方资料(仅供参考)
【英文名称】Reglan
【适用证】
- 对未能对常规治疗有反应的成人进行4至12周有症状的记录性胃食管反流治疗(1)
- 急性和复发性糖尿病胃轻瘫成人症状的认识(1)
【禁忌症】
TD的历史或对甲氧氯普胺的肌张力障碍反应(4)
当刺激肠胃蠕动可能是危险的时(4)
嗜铬细胞瘤,释放儿茶酚胺的副神经节瘤(4)
癫痫(4)
对甲氧氯普胺的超敏反应(4)
【用法用量】
胃食管反流(2.2)
持续或间歇地管理Reglan:
○连续:给予10至15毫克,每餐前30分钟和就寝时间(最多每天60毫克),持续4至12周。
○间歇性:在引发情况之前单次剂量高达20 mg
急性和复发性糖尿病性胃轻瘫(2.3)
每餐前30分钟和睡前(每天最多40毫克)服用10毫克,持续2至8周
特定人群的剂量调整(2.2,2.3)
对于胃食管反流和急性和复发性糖尿病胃轻瘫,请参阅完整处方信息,了解老年患者,中度或重度肝脏或肾脏损害患者以及细胞色素P450 2D6(CYP2D6)代谢不良者的剂量减少情况
【INDICATIONS AND USAGE】
Reglan tablets are indicated for the:
-Treatment for 4 to 12 weeks of symptomatic, documented gastroesophageal reflux in adults who fail to respond to conventional therapy (1)
-Relief of symptoms in adults with acute and recurrent diabetic gastroparesis (1)
【DOSAGE AND ADMINISTRATION】
Gastroesophageal Reflux (2.2)
Administer Reglan continuously or intermittently:
○ Continuous: Administer 10 to 15 mg, 30 minutes before each meal and at bedtime (maximum of 60 mg per day) for 4 to 12 weeks.
○ Intermittent: Single doses up to 20 mg prior to provoking situation
Acute and Recurrent Diabetic Gastroparesis (2.3)
Administer 10 mg, 30 minutes before each meal and at bedtime (maximum of 40 mg per day) for 2 to 8 weeks
Dosage Adjustment in Specific Populations (2.2, 2.3)
For gastroesophageal reflux and acute and recurrent diabetic gastroparesis, see Full Prescribing Information for recommended dosage reductions for elderly patients, in patients with moderate or severe hepatic or renal impairment, and cytochrome P450 2D6 (CYP2D6) poor metabolizers
【CONTRAINDICATIONS】
History of TD or dystonic reaction to metoclopramide (4)
When stimulation of gastrointestinal motility might be dangerous (4)
Pheochromocytoma, catecholamine-releasing paragangliomas (4)
Epilepsy (4)
Hypersensitivity to metoclopramide (4)
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201921323100913.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- |