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  药店国别: 美国药房
产地国家: 美国
所属类别: 心血管系统药物->抗心绞痛药物
处方药:处方药
包装规格: 2.5毫克/胶囊 100胶囊/盒
计价单位:
   
生产厂家英文名:
Actavis
该药品相关信息网址1:
http://www.drugs.com/pro/dynacirc.html
该药品相关信息网址2:
http://www.rxlist.com/dynacirc_cr-drug.htm
原产地英文商品名:
ISRADIPINE CAPSULE(DYNACIRC GENERIC)2.5mg/cap 100caps/box
原产地英文药品名:
ISRADIPINE
原产地英文化合物名称:
4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester
中文参考商品译名:
伊拉地平胶囊剂(导脉顺仿制药)2.5毫克/胶囊 100胶囊/盒
中文参考药品译名:
伊拉地平
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Hypertension
英文适应病症2:
Coronary heart disease
英文适应病症3:
Angina
英文适应病症4:
Congestive Heart Failure
临床试验期:
完成
中文适应病症参考翻译1:
高血压
中文适应病症参考翻译2:
冠心病
中文适应病症参考翻译3:
心绞痛
中文适应病症参考翻译4:
充血性心力衰竭
药品信息:

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 详细处方信息以本药内容附件PDF文件(2010102423363616.pdf)的“原文Priscribing Information”为准
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部分中文依拉地平处方资料(仅供参考)

【药物名称】导脉顺

【别名】依拉地平,易拉地平,导脉顺,伊拉地平

【外文名】Isradipine, -200-110,COMIR,PRESCAL,DYNACIRC,Vascal

【别  名】4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester

【药理及应用】为二氢吡啶类钙拮抗药,对血管的选择性高,能舒张外周血管、冠状血管和脑血管,对心脏的作用较小,仅抑制窦房结的自发活动。可使血压下降,生效较慢(2~4周),持续时间较久。口服后吸收良好,由于首过效应明显,生物利用率仅17%。口服后血药浓度峰时间为2小时,在血浆中与蛋白的结合率为95%。在肝中代谢。t1/2约9小时。 用于高血压、冠心病和心绞痛,也可用于充血性心力衰竭。

【用法用量】口服,1次2.5mg,1日2次;必要时可将剂量递增至1次5mg,1日2次。

【不良反应】毒副作用小,每次2.5~5mg耐受良好,剂量增加副作用也增加。常见的副作用有头痛、眩晕、心悸、潮红、水肿、疲劳和腹部不适等。一般轻微,且停药即可消失。

【禁忌症】孕妇和哺乳妇女用药安全性尚未建立,最好禁用;主动脉瓣狭窄、窦房结病综合征、低收缩压患者应慎应。

【注意事项】其不良反应主要是由于血管舒张所致的头痛、眩晕、心悸、面部潮红等。偶见肝功异常,且为时短暂。有时出现胃肠道不适等。主动脉狭窄、窦房结病综合征及低收缩压患者慎用。用于心绞痛时,勿突然停药。

DynaCirc CR®
(isradipine) Controlled Release Tablets

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DynaCirc CR Oral Uses
Isradipine is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Isradipine is called a calcium channel blocker. It works by relaxing blood vessels so blood can flow more easily.

How to use DynaCirc CR Oral
Take this medication by mouth, usually once daily with or without food or as directed by your doctor. Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.

The dosage is based on your medical condition and response to treatment. Your doctor may gradually increase your dose. Follow your doctor's instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take 2 to 4 weeks before you get the full benefit of this drug.

Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase).

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DynaCirc CR Oral Side Effects
Dizziness, nausea, headache, tiredness, flushing and swelling of the ankles/feet may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

An empty tablet shell may appear in your stool. This is harmless since your body has already absorbed the medication.

To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, fast/irregular/pounding heartbeat.

Tell your doctor immediately if any of these rare but very serious side effects occurs: severe abdominal pain/constipation, vision changes.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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DynaCirc CR Oral Precautions
Before taking isradipine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain structural heart problems (aortic stenosis).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, stomach/intestine problems (such as narrowing, blockage).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist that you are taking this medication.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

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DynaCirc CR Oral Interactions
See also the How to Use section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.

Other medications can affect the removal of isradipine from your body, which may affect how isradipine works. Examples include cimetidine, azole antifungals (such as itraconazole), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

Cimetidine is a nonprescription drug that is commonly used to treat extra stomach acid. Because cimetidine may interact with isradipine, ask your pharmacist about other products to treat stomach acid.

Check the labels on all your medicines (such as cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure (such as pseudoephedrine, phenylephrine, ibuprofen, naproxen). Ask your pharmacist about using these products safely.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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DynaCirc CR Oral Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES:
Do not share this medication with others. Talk with your doctor about making changes to your lifestyle that may help this medication work better (such as stress reduction programs, exercise, and dietary changes).

Laboratory and/or medical tests (such as liver function tests, blood pressure, electrocardiograms) may be performed from time to time to monitor your progress or check for side effects. Consult your doctor for more details.

There are different types of this medication available. They may not have the same effects. Do not change types without consulting your doctor or pharmacist.

Have your blood pressure checked regularly while taking this medication. Discuss with your doctor how to monitor your own blood pressure.

MISSED DOSE:
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:
Store at room temperature below 86 degrees F (30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

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 详细处方信息以本药内容附件PDF文件(2010102423363616.pdf)的“原文Priscribing Information”为准
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更新日期: 2014-09-17
附件:


2010102423363616.pdf    

 
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