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  药店国别: 美国药房
产地国家: 美国
所属类别: 神经系统药物->镇痛药
处方药:处方药
包装规格: 60毫克/胶囊 100胶囊/瓶
计价单位:
  点击放大  
生产厂家中文参考译名:
KING PHARMS
生产厂家英文名:
KING PHARMS
该药品相关信息网址1:
www.avinza.com/
该药品相关信息网址2:
www.drugs.com/avinza.html
该药品相关信息网址3:
www.rxlist.com/avinza-drug.htm
原产地英文商品名:
AVINZA 60mg/Capsule 100Capsules/bottle
原产地英文药品名:
MORPHINE SULFATE
中文参考商品译名:
AVINZA 60毫克/胶囊 100胶囊/瓶
中文参考药品译名:
硫酸吗啡
原产地国家批准上市年份:
2002/03/20
英文适应病症1:
Pain
临床试验期:
完成
中文适应病症参考翻译1:
疼痛
药品信息:

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 详细处方信息以本药内容附件PDF文件(20125823111021.PDF,200952504194340.pdf)的“原文Priscribing Information”为准
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部分中文AVINZA处方资料(仅供参考)

主题:AVINZA
    Ligand Pharma近日宣布:公司签署了出售AVINZA相关资产的协议,将AVINZA相关资产转让给King Pharmaceuticals,出售价包括3.13亿美元的头期款与2017年11月到期的专利权权利金协议。扣除当前权利金义务,King Pharmaceuticals将在完成交易后的20个月内支付权利金的15%给Ligand Pharma。
    AVINZA是每天用药一次的硫酸吗啡缓释口服胶囊,用于长期需要持续使用阿片类药物进行治疗的中度至重度慢性疼痛患者。在同类产品中,AVINZA是最先问世的药品,于2002年3月通过了FDA的批准。2005年,AVINZA销售额为1.79亿美元。

易兰公司的Avinza在美国获得批准
易兰公司的吗啡类产品Avinza(硫酸吗啡缓释剂,以前称Morphelan)获得了美国FDA的批准,该药物(每天一次用药)的适用对象为那些需要长期持续治疗的慢性中度和重度疼痛患者。该产品将于第二季度在美国上市,其销售由Ligand制药公司负责,该公司拥有其在美国和加拿大的销售权。易兰公司声称,他们仍然保留Avinza在世界其它地方的销售权,但在一些主要地区的申请工作仍然悬而未决。Avinza是一种利用易兰的SODAS技术生产的含有吗啡成份的控释胶囊,内部包含有立即释放和持续释放的吗啡小球。其设计技术保证了血浆的吗啡浓度在一个相当长的时期内保持在治疗范围。

IMPORTANT SAFETY INFORMATION
AVINZA® (morphine sulfate extended-release capsules) is a prescription drug that contains morphine. Each AVINZA® Capsule contains enough morphine to last for 24 hours and should be taken once a day. AVINZA® is for adults 18 years or older with moderate to severe pain who need around-the-clock, nonstop treatment for an extended period of time.
•AVINZA® Capsules are to be swallowed whole. DO NOT chew, crush, or dissolve the beads in capsules before swallowing. If the beads are chewed, crushed, or dissolved, the entire 24-hour dose may be absorbed into your body all at once. This can lead to serious problems, including overdose and death
•If you have trouble swallowing the capsules, you may open them and sprinkle all of the beads on a small amount of applesauce just before swallowing. Make sure to swallow all of the beads whole
•Do not drink alcoholic beverages while using AVINZA®, or use prescription or nonprescription medications that contain alcohol. Consuming alcohol while taking AVINZA® may cause the rapid release and absorption of a potentially deadly dose of morphine
•Because AVINZA® may make you sleepy, you should not drive, operate heavy machinery, or perform any other possibly dangerous activities until you know how you react to AVINZA®
•AVINZA® should not be given to anyone other than the person for whom it was prescribed

Tell your healthcare professional about the following:
•Any and all other health or medical problems you may have
•All medicines (prescription and nonprescription) and vitamins you are taking. Do not take other medicines without your healthcare professional’s approval
•If you are pregnant or plan to become pregnant
•If you are breastfeeding, because morphine will pass through the milk and may harm the baby
•If you have abused drugs in the past. There is a risk of abuse or addiction with all opioid medications. You may have a higher chance of developing an abuse problem or addiction again while using AVINZA®

AVINZA® is not for everyone. Only you and your healthcare professional can know if AVINZA® is right for you.
Make sure to follow your healthcare professional’s directions exactly.
•Do not change your dose unless your healthcare professional tells you to change it
•Do not take AVINZA® more often than prescribed. You should not stop taking AVINZA® all at once if you have been taking it for more than a few days. Your healthcare professional can instruct you on how to stop taking this medicine slowly to avoid uncomfortable symptoms

Constipation is a common side effect of medicines that contain morphine, including AVINZA®. When you start taking AVINZA®, discuss steps to prevent or relieve constipation with your healthcare professional. Other common side effects of AVINZA® are nausea, drowsiness, headache, and itching. Some of these side effects may decrease with continued use.

Keep AVINZA® in a secure place and out of the reach of children. Protect from theft. When AVINZA® is no longer needed, the unused capsules should be destroyed by flushing them down the toilet.

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 详细处方信息以本药内容附件PDF文件(20125823111021.PDF,200952504194340.pdf)的“原文Priscribing Information”为准
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更新日期: 2012-5-9
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