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  药店国别: 美国药房
产地国家: 美国
所属类别: 抗微生物药物->其他抗生素
处方药:处方药
包装规格: 300毫克/胶囊 100胶囊/瓶
计价单位:
   
该药品相关信息网址1:
http://www.cleocin.com/
该药品相关信息网址2:
http://www.rxlist.com/clindamycin-drug.htm
该药品相关信息网址3:
http://www.medicinenet.com/clindamycin-oral/article.htm
原产地英文商品名:
CLINDAMYCIN HCL(CLEOCIN GENERIC) 300mg/cap 100caps/bottle
原产地英文药品名:
CLINDAMYCIN HCL
中文参考商品译名:
盐酸克林霉素(丽欧迅仿制药) 300毫克/胶囊 100胶囊/瓶
中文参考药品译名:
盐酸克林霉素
中文参考化合物名称:
6-(1-甲基-反-4-丙基-L-2-吡咯烷甲酰氨基)-1-硫代-7(S)-氯-6,7,8-三脱氧-L-苏式-α-D-半乳辛吡喃糖苷-2-棕榈酸酯盐酸盐
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Antibacterial
英文适应病症2:
Anti-infective
临床试验期:
完成
中文适应病症参考翻译1:
抗菌
中文适应病症参考翻译2:
抗感染
药品信息:

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 详细处方信息以本药内容附件PDF文件(20109221471526.pdf)的“原文Priscribing Information”为准
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部分中文盐酸克林霉素处方资料(仅供参考)

药品名称
通用名:盐酸克林霉素棕榈酸酯   
英文名:Clindamycin Palmitate Hydrochloride 本品主要成份为盐酸克林霉素棕榈酸酯
化学名为:6-(1-甲基-反-4-丙基-L-2-吡咯烷甲酰氨基)-1-硫代-7(S)-氯-6,7,8-三脱氧-L-苏式-α-D-半乳辛吡喃糖苷-2-棕榈酸酯盐酸盐。   
分子式:C34H63ClN2O6S?HCl   
分子量:699.87 本品为白色或类白色片。

药理毒理
  盐酸克林霉素棕榈酸酯系克林霉素的衍生物,体外无抗菌活性,在体内经酯酶水解形成克林霉素而发挥抗菌活性。克林霉素作用机制为抑制细菌蛋白质的合成,主要作用于革兰阳性球菌和厌氧菌感染。   
    本品对金黄色葡萄球菌和表皮葡萄球菌、肺炎链球菌、化脓性链球菌等均有较好的抗菌作用,流感嗜血杆菌及淋病奈瑟氏球菌对本品呈中度敏感。部分耐红霉素的金黄色葡萄球菌、表皮葡萄球菌对本品仍敏感。   
    本品对革兰阴性和革兰阳性厌氧菌均有较好的抗菌作用,其中对脆弱拟杆菌的MIC50和MIC90分别为0.062和0.5mg/L,对消化链球菌MIC50和MIC90分别为0.125和4mg/L。

适应症
革兰阳性菌引起的下列各种感染性疾病:   
1.扁桃体炎、化脓性中耳炎、鼻窦炎等;   
2.急性支气管炎、慢性支气管炎急性发作、肺炎、肺脓肿和支气管扩张合并感染等;   
3.皮肤和软组织感染:疖、痈、脓肿、蜂窝组织炎、创伤和手术后感染等;   
4.泌尿系统感染:急性尿道炎、急性肾盂肾炎、前列腺炎等;   
5.其他:骨髓炎、败血症、腹膜炎和口腔感染等;   
厌氧菌引起的各种感染性疾病:   
1.脓胸、肺脓肿、厌氧菌性肺炎;   
2.皮肤和软组织感染、败血症;   
3.腹内感染:腹膜炎、腹腔内脓肿;   
4.女性盆腔及生殖器感染:子宫内膜炎、非淋球菌性输卵管及卵巢脓肿、盆腔蜂窝组织炎及妇科手术后感染等。  

用法用量
    温开水送服,或温开水溶解后服用。 
    按克林霉素计,儿童日剂量为8-25mg/kg(一般感染8-16mg/kg,重症感染17-25mg/kg),分3-4次服用(体重10kg以下幼儿每次服药应不少于37.5mg,一日3次);成人每次150-300mg(重症感染可用450mg),一日4次。即成人每次2-4片(重症感染可用6片),一日4次。或遵医嘱。 

禁忌:对林可霉素类及林可霉素过敏者禁用。 

贮藏:密封保存。

GENERIC NAME: CLINDAMYCIN - ORAL (klin-da-MY-sin)
BRAND NAME(S): Cleocin

WARNING: This medication should be used only for serious bacterial infections because it can sometimes cause a severe (rarely fatal) intestinal condition (pseudomembranous colitis) due to a resistant bacteria. This condition may occur during treatment or even weeks after treatment has stopped. Tell your doctor immediately if you develop persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool. Do not use anti-diarrhea products or narcotic pain medications if you have these symptoms because these products may make them worse. Consult your doctor or pharmacist for details and an appropriate treatment plan.

USES: Clindamycin is used to treat a wide variety of serious bacterial infections. It is an antibiotic which works by stopping the growth of bacteria. This antibiotic only treats bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

HOW TO USE: Take this medication by mouth with or without food, usually 4 times a day (every 6 hours), or as directed by your doctor. Take it with a full glass of water (8 ounces or 240 milliliters) unless your doctor directs you otherwise. Do not lie down for at least 30 minutes after taking this drug. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Inform your doctor if your condition persists or worsens.

SIDE EFFECTS: Nausea, vomiting, upset stomach, or mild diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: sore/painful throat, joint pain/swelling, yellowing eyes or skin. See also the Warning section. Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking clindamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin, tartrazine yellow dye or aspirin; or if you have any other allergies. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain intestinal condition (pseudomembranous colitis). Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe liver disease, severe kidney disease, other intestinal diseases (e.g., enteritis, ulcerative colitis), chronic asthma or hay fever (atopic conditions). Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially persistent diarrhea. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: erythromycin, kaolin-pectin, live bacterial vaccines. Clindamycin may increase the effects of certain drugs used during surgery (neuromuscular blockers such as pancuronium, tubocurarine). Tell your doctor if you are going to be having any surgeries while using this medication.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases. With prolonged use, laboratory and/or medical tests (e.g., kidney and liver function tests, blood counts) should be performed to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store the US product at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Store the Canadian product at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

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 详细处方信息以本药内容附件PDF文件(20109221471526.pdf)的“原文Priscribing Information”为准
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更新日期: 2013-08-06
附件:
 
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