您好,欢迎光临世界标品! 登录 注册(订药物标准品请用邮件联系我们)

中国医药研发对照标品提供商
Non-clinical Research-used
Medicine Sample Provider

当前本网站药物产品种数共 8050 处方药 7676 非处方药 258 保健品/医疗用具 116

世界标品医药目录搜索(中英文):
世界各国官方药品目录搜索(英文):
世界标品医药知识搜索(中英文):

联系方式
国际免费电话:
QQ客服1:1793093587
QQ客服2:1586083059
QQ客服3:2786706041
QQ客服6:2992753224
QQ客服7:2394834588

咨询邮箱:
scimed.shanghai@shijiebiaopin.com
info@shijiebiaopin.com
pharmacy.shijiebiaopin1@gmail.com
pharmacy.shijiebiaopin2@gmail.com

  药店国别: 加拿大药房
产地国家: 新西兰
所属类别: 神经系统药物->帕金森症
处方药:处方药
包装规格: (200/50)毫克/片 100片/瓶
计价单位:
  点击放大  
生产厂家中文参考译名:
百时美施贵宝
生产厂家英文名:
BRISTOL MYERS SQUIBB
该药品相关信息网址1:
http://www.drugs.com/cdi/sinemet.html
该药品相关信息网址2:
http://www.rxlist.com/sinemet-drug.htm
该药品相关信息网址3:
http://www.medicinenet.com/levodopa_with_carbidopa-oral/page2.htm
原产地英文商品名:
SINEMET CR (200/50)mg/tab 100tabs/bottle
原产地英文药品名:
LEVODOPA/CARBIDOPA
中文参考商品译名:
息宁 CR (200/50)毫克/片 100片/瓶
中文参考药品译名:
左旋多巴/卡比多巴
原产地国家批准上市年份:
1991/05/30
英文适应病症1:
Parkinson's disease
英文适应病症2:
Paralysis agitans
英文适应病症3:
Paralysis agitans syndrome
临床试验期:
完成
中文适应病症参考翻译1:
帕金森病
中文适应病症参考翻译2:
震颤麻痹
中文适应病症参考翻译3:
震颤麻痹综合征
药品信息:

---------------------------------------------------------------
 详细处方信息以本药内容附件PDF文件(2010122819492615.pdf)的“原文Priscribing Information”为准
---------------------------------------------------------------
部分中文息宁处方资料(仅供参考)

英文药名: Sinemet (Carbidopa/Levodopa)

中文药名: 息宁(卡比多巴~左旋多巴)

药品名称
药物名称:息宁
英文名:Sinemet
别名:息宁,心宁美, 卡比多巴-左旋多巴, 息宁控释片, 帕金宁控释片
外文名:Carbidopa and Levodopa, Sinemet
类别:抗帕金森病药

药理毒理
神经内科用药。
本药是卡比多巴(一种芳香氨基酸类脱羧酶抑制剂)与左旋多巴(多巴胺的前体药物)的复合物,是以聚合物为基质的控释片剂。左旋多巴在脑内通过脱羧形成多巴胺而缓解帕金森氏病的症状。不能透过血脑屏障的卡比多巴只抑制外周左旋多巴的脱羧,从而使更多的左旋多巴转运到脑,转化成多巴氨,避免了左旋多巴频繁大剂量给药的必要性。低剂量减少或可能有助于消除胃肠道和心血管系统的副作用,尤其是那些与外周形成多巴胺有关的副作用。控释片在4-6小时内释放出有效成分。本药的血浆左旋多巴水平变化较小。

适应症
震颤麻痹,震颤麻痹综合征。

用法用量
口服,0.5~1片/次,2~4次/日,按病情需要逐渐增量,一般每日不超过卡比多巴75mg,左旋多巴750mg。
任何疑问,请遵医嘱!

不良反应
常见运动障碍、恶心、呕吐、抑郁、失眠和幻觉等,偶有消化道出血。

药物相互作用
与单胺氧化酶抑制药合用可致血压骤升。
吩塞秦、可乐定、罂粟碱、利舍平、苯妥英等可拮抗本品的作用。
溴隐亭可增强本品作用。

注意事项
妊娠C类。狭角型青光眼、皮肤癌患者禁用。
有心、肝、肺、肾、消化道溃疡及精神障碍者慎用。

规格
心宁美,(息宁控释片Sinemet):
卡比多巴25mg+左旋多巴100mg
卡比多巴10mg+左旋多巴100mg
卡比多巴50mg+左旋多巴200mg
卡比多巴50mg+左旋多巴250mg。

GENERIC NAME: CARBIDOPA/LEVODOPA - ORAL (car-beh-DOE-puh/lee-voh-DOE-puh)
BRAND NAME(S): Atamet, Sinemet

USES: Levodopa and carbidopa are used in combination to treat the symptoms of Parkinson's disease or Parkinson-like symptoms (e.g., shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a naturally occurring substance (dopamine) in the brain. Levodopa changes into dopamine in the brain, helping to control movement.Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. This can reduce some of levodopa's side effects such as nausea and vomiting, and it may also allow your doctor to increase your levodopa dose more quickly to find the best dose for you. This combination may be used alone or with other drugs for Parkinson's disease.

HOW TO USE: Take this medication by mouth with food, usually 3 to 4 times a day or as directed by your doctor. If you have been taking levodopa without any carbidopa and are taking this combination for the first time, wait at least 12 hours after your last levodopa dose before starting this medication. You may want to start your first dose in the morning. Your doctor will usually reduce your levodopa dose when starting this combination to prevent side effects from too much dopamine. Be sure to follow your doctor's instructions closely.This combination comes in different strengths with different amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor may also prescribe carbidopa alone to be taken with this combination.Avoid high-protein diets because they may prevent absorption of this medication. Separate your dose of this medication as many hours as possible from any iron supplements or products containing iron (e.g., multivitamins with minerals) you may take. Iron can reduce the amount of carbidopa and levodopa available to the body.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Dosage is based on your medical condition and response to therapy.Some people may experience a decrease in the effectiveness of this medication just before the next dose is due. If this occurs and is bothersome, notify your doctor. Do not change your dose of this or any other medication without checking with your doctor first.Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also Side Effects section.)Inform your doctor if your condition does not improve or if it worsens.

SIDE EFFECTS: Dizziness, nausea, vomiting, trouble sleeping, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.This medication may cause your urine, sweat or saliva to turn red, brown, or black. This is harmless, but your clothes may become discolored.Tell your doctor immediately if any of these unlikely but serious side effects occur: greatly increased eye blinking/twitching, irregular heartbeat, fainting, mental/mood changes (e.g., confusion, depression, hallucinations, thoughts of suicide), worsening of involuntary movements/spasms.Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, signs of infection (e.g., fever, persistent sore throat), tingling of the hands/feet, vision changes (e.g., blurred/double vision).Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, seizures, vomit that looks like coffee grounds, black/tarry stools.Abruptly stopping or reducing the dose of this medication may rarely cause a serious (sometimes fatal) condition (neuroleptic malignant syndrome). Seek immediate medical attention if any of these rare but very serious side effects occur: fast/shallow breathing, confusion, severe dizziness/fainting, high fever, unusual muscle stiffness, unusual sweating.For males, in the very unlikely event you have a painful or prolonged erection (lasting more than 4 hours), stop using this drug and seek immediate medical attention or permanent problems could occur.A very serious allergic reaction is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain eye problem (narrow-angle glaucoma).Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding disorders, breathing problems (e.g., asthma, emphysema), certain eye problem (wide-angle glaucoma), heart or blood vessel problems (e.g., arrhythmias, heart attack, angina), kidney disease, liver disease, mental/mood disorders (e.g., depression, schizophrenia), peptic ulcer, seizure.This drug may make you dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.To minimize lightheadedness, get up slowly when rising from a sitting or lying position.Before having surgery, tell your doctor or dentist that you are taking this medication.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.Levodopa may pass into breast milk and affect milk production. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: See also How to Use Section.Your healthcare professional (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not stop or change the dosage of any medicine without checking with them first.This drug should not be used with the following medication because a very serious interaction may occur: tetrabenazine.Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, tranylcypromine) within 2 weeks before, during, and after treatment with this medication. In some cases a serious (possibly fatal) drug interaction may occur.Certain MAO inhibitors (selegiline, rasagiline) may be used cautiously with close monitoring by your doctor.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting carbidopa/levodopa. If you are taking selegiline or rasagiline for Parkinson's disease, ask your doctor if you should continue taking it.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: other drugs to treat Parkinson's disease (e.g., all levodopa-containing products, benztropine, entacapone), medicine for high blood pressure (e.g., guanethidine, methyldopa, reserpine), antidepressants (e.g., tricyclics such as amitriptyline/nortriptyline), antipsychotics (e.g., chlorpromazine, thioridazine, risperidone), metoclopramide, phenytoin, papaverine, certain sedatives (e.g., benzodiazepines such as chlordiazepoxide/diazepam), tryptophan (e.g., l-tryptophan, oxitriptan).This medication may interfere with certain laboratory tests (including urine catecholamine/glucose/ketone tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: irregular heartbeat, muscle spasms, convulsions.

NOTES: Do not share this medication with others.Laboratory and/or medical tests (e.g., blood count, heart/kidney/liver function) may be performed to monitor your progress.People with Parkinson's disease may have an increased risk for developing skin cancer (melanoma). Tell your doctor promptly if you notice a change in the appearance or size of moles or other unusual skin changes. Ask your doctor if you should have regular skin exams.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 59-86 degrees F (15-30 degrees C). Store in a tightly closed container away from high heat, moisture, and light. Levodopa may turn a darker color when not properly stored. If this occurs, it may not work as well and may need to be thrown out and replaced. Consult your pharmacist for more information on what to do if the medication changes color. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

---------------------------------------------------------------
 详细处方信息以本药内容附件PDF文件(2010122819492615.pdf)的“原文Priscribing Information”为准
---------------------------------------------------------------

更新日期: 2011-7-15
附件:
2010122819492615.pdf    







 
调控比例: 100%
订购表单下载
Copyrights © 2010,2011,2012 www.ShiJieBiaoPin.com, Inc., All rights Reserved www.ShiJieBiaoPin.com, Inc.
客服工作时间:太平洋时间18:00-24:00
国际免费电话:
友情提示:以上电话为免费电话,无需您承担任何费用,世界标品提供中文客服,请您放心拨打!
电子邮箱:info.shijiebiaopin.com@gmail.com, info@shijiebiaopin.com