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  药店国别: 德国药房
产地国家: 德国
所属类别: 耳鼻喉及口腔科药物->鼻塞
处方药:处方药
包装规格: 10克/管
计价单位:
  点击放大  
生产厂家中文参考译名:
stada
生产厂家英文名:
stada
该药品相关信息网址1:
http://www.stada.de/
原产地英文商品名:
GRIPPOSTAD-RINO 0.05%-10.0 10g/tube
原产地英文药品名:
XYLOMETAZOLINE HCL
原产地英文化合物名称:
2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride; Xylometazoline HCL
中文参考商品译名:
GRIPPOSTAD-RINO 0.05%-10.0 10克/管
中文参考药品译名:
盐酸赛洛唑啉
中文参考化合物名称:
2-(4-叔丁基-2,6-二甲基苄基)-2-咪唑啉盐酸盐
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Stuffy nose
临床试验期:
完成
中文适应病症参考翻译1:
鼻塞
药品信息:

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 部分中文盐酸赛洛唑啉处方资料(仅供参考)
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中文名称:盐酸赛洛唑啉鼻用胶凝   

别名:2-(4-叔丁基-2,6-二甲基苄基)-2-咪唑啉盐酸盐   

英文名称:xylometazoline hcl   

英文别名:2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazolinmonohydrochloride; 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-1h-imidazol; otrivinehydrochloride; otrivinhydrochloride; XYLOMETAZOLINE HYDROCHLORIDE; XYLOMETAZOLIN HYDROCHLORIDE; 2-(4-TERT-BUTYL-2,6-DIMETHYLBENZYL)-2-IMIDAZOLINE HYDROCHLORIDE

英文名:Xylometazoline Hydrochloride Nasal GEL

作用类别:为耳鼻喉科用药类非处方药药品

药理毒理:本品为α-肾上腺素能受体激动药,具有收缩鼻粘膜血管的作用,从而改善鼻塞症状。

适应症:用以减轻急慢性鼻炎、鼻窦炎、过敏性鼻炎、肥厚性鼻炎等疾病引起的鼻塞症状。

用法和用量:成人滴用0.1%溶液,一次2~3滴,一日2次。6~12岁儿童滴用0.05%溶液,一次2~3滴,一日2次。幼儿禁用。

不良反应:偶见鼻腔内有一过性的轻微烧灼感、干燥感、头痛、头晕、心律加快等反应。

禁忌:
1.接受单胺氧化酶(MAO)抑制剂或三环类抗抑郁剂治疗的患者和对本品过敏者、幼儿禁用。   
2.有冠心病、高血压、甲状腺机能亢进、糖尿病、狭角性青光眼的患者和孕妇慎用。   
3.萎缩性鼻炎及鼻腔干燥者禁用。

注意事项:不宜长期连续应用,每次连续使用时间不宜超过7天。

药物相互作用:使用本品时不能同时使用其他收缩血管类滴鼻剂。

贮藏:遮光,密闭保存。

Grippostad-Rino nasal gel 0,05% 10gr

Package: 1 tube 10 g

Producer: Germany

xylometazoline hydrochloride
Synonyms:
2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride; Xylometazoline HCL

Xylometazoline
Xylometazoline (also known as xylomethazoline) is a drug which is used as a topical nasal decongestant.[1] It is applied directly into the nose, either as a spray or as drops.

Xylometazoline is marketed under many brand names (see below), with the typical adult dose being 0.1% w/v xylometazoline, and the dose for children under 12 being 0.05%.

Mechanism of action
The drug works by constricting the blood vessels in the nose. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made. (If the colour of the nasal passage is observed, it is visibly paler after dosage.)

Xylometazoline is an imidazole derivative which is designed to mimic the molecular shape of adrenaline. It binds to alpha-adrenergic receptors in the nasal mucosa.[2] Due to its sympathomimetic effects, it should not be used by people with high blood pressure, or other heart problems.

Extended usage of xylometazoline can result in decreased effectiveness or a build up of tolerance against the drug.[3] The number of receptors decreases, and when the administration of the drug is ceased, chronic congestion can occur; this is called rhinitis medicamentosa, commonly referred to as rebound congestion. Moreover long-term overdosing can cause degenerative changes in nasal mucous membranes that pose another health problem.

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2010-10-29更新

更新日期: 2010-10-29
附件:
 
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