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当前本网站药物产品种数共 8524 处方药 8148 非处方药 269 保健品/医疗用具 107

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  药店国别: 美国药房
产地国家: 美国
所属类别: 作用于消化系统药物->溃疡性结肠炎
处方药:处方药
包装规格: 800毫克/片 180片/盒
计价单位:
  点击放大  
生产厂家中文参考译名:
WARNER CHILCOTT LLC
生产厂家英文名:
WARNER CHILCOTT LLC
该药品相关信息网址1:
http://www.asacol.com/
该药品相关信息网址2:
http://www.drugs.com/asacol.html
该药品相关信息网址3:
http://www.rxlist.com/asacol-drug.htm
原产地英文商品名:
ASACOL HD DR TABLET 800mg/tab 180tabs/box
原产地英文药品名:
MESALAMINE
中文参考商品译名:
ASACOL HD缓释片 800毫克/片 180片/盒
中文参考药品译名:
MESALAMINE
原产地国家批准上市年份:
2008/05/29
英文适应病症1:
Colonic ulcers
英文适应病症2:
Colitis
临床试验期:
完成
中文适应病症参考翻译1:
结肠溃疡
中文适应病症参考翻译2:
结肠炎
药品信息:

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 详细处方信息以本药内容附件PDF文件(201081722025922.pdf)的“原文Priscribing Information”为准
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部分中文ASACOL处方资料(仅供参考)

    与安慰剂对照组相比较,更多的溃疡性结肠炎患者每天使用1.5克mesalamine进行治疗之后在6个月内病情未出现复发,获得这种疗效的患者数量达到统计显著性水平。
 
    mesalamine含有针对肠部给药并取决于Ph值的包衣(可以延迟药物的释放)和一种聚合物(起缓释作用)。这种延迟+放缓药物释放的组合成分可以切实保证mesalamine/5-ASA(5-氨基水杨酸)能够从进入小肠时再开始给药,并且让给药过程贯穿结肠。

适应症
适用于结肠溃疡、结肠炎的治疗。

用法用量
口服,成人一般用量1-2片/次,一日3次。对于轻、中度的急症可增加到12片/日,或遵医嘱。

不良反应
与少数不能耐受柳氮磺胺吡啶的病人类似,主要副作用有恶心、腹泻、腹痛、胃烧灼感、纳差、腹胀、腰痛、便秘、月经不调和个别报道的头痛。以往服用柳氨磺胺吡啶使结肠炎病情加重者亦应在使用本品前予考虑。罕有报导出现白细胞减少、血小板减少、中性白细胞减少、胰腺炎、肝炎、心包炎、心肌炎、牙槽炎、急性间质性肾炎、肾病综合症及肾衰,停药后各种症状即消失。治疗期间出现肾衰迹象,应考虑药物导致肾中毒的可能性。未发现在服用柳氮磺胺吡啶时出现的骨髓抑制、精子量减少及活动度抑制的情况。

禁忌
即往对水杨酸类药有过敏史者禁用;严重的肾功能损害者禁用(肾小球滤过率<2Oml/分)。

规格
0.4g, 0.8g

贮藏
遮光,密闭,于25℃以下保存。

Asacol
Generic Name: mesalamine (oral) (me SAL a meen)
Brand Names: Asacol, Lialda, Pentasa

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What is Asacol?
Asacol (mesalamine) affects a substance in the body that causes inflammation, tissue damage, and diarrhea.

Asacol is used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Asacol is also used to prevent the symptoms of ulcerative colitis from recurring.

Asacol may also be used for other purposes not listed in this medication guide.

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Important information about Asacol
You should not use Asacol if you are allergic to mesalamine or to aspirin or other salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others).

Before you take Asacol, tell your doctor if you have kidney or liver disease, a stomach condition called pyloric stenosis, a heart condition such as congestive heart failure, or a history of allergy to sulfasalazine (Azulfidine).

Do not crush, break, or chew a Asacol tablet. Swallow the tablet whole. It is specially formulated to release the medicine after it has passed through your stomach into your intestines.

Call your doctor if you find undissolved tablets in your stool.

Stop using Asacol and call your doctor at once if you have severe stomach pain, cramping, fever, headache, and bloody diarrhea.

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What should I discuss with my healthcare provider before taking Asacol?
You should not use Asacol if you are allergic to mesalamine or to aspirin or other salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others).

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Asacol:
a stomach condition called pyloric stenosis;
a history of allergy to sulfasalazine (Azulfidine);
a heart condition such as congestive heart failure;
kidney disease; or
liver disease.

FDA pregnancy category B. Asacol is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Mesalamine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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How should I take Asacol?
Take Asacol exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take Asacol with a full glass of water.

Asacol can usually be taken with or without food. Follow your doctor's instructions.

Do not crush, break, or chew a Asacol tablet. Swallow the tablet whole.

The enteric-coated tablet has a special coating to protect your stomach. Breaking the pill could damage this coating.

Call your doctor if you find undissolved tablets in your stool.

Store Asacol at room temperature away from moisture and heat.

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What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

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What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include ringing in your ears, dizziness, headache, confusion, drowsiness, sweating, shortness of breath, vomiting, and diarrhea.

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What should I avoid while taking Asacol?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Asacol.

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Asacol side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Asacol and call your doctor at once if you have any of these serious side effects:
severe stomach pain, cramping, fever, headache, and bloody diarrhea.

Less serious side effects may include:
mild nausea, vomiting, stomach cramps, diarrhea, gas;
fever, sore throat, or other flu symptoms;
constipation;
headache or dizziness;
tired feeling; or
skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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What other drugs will affect Asacol?
Before taking Asacol, tell your doctor if you are using any of the following drugs:
azathioprine (Imuran) or mercaptopurine (Purinethol);
pentamidine (Nebupent, Pentam);
tacrolimus (Prograf);
amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet);
antibiotics such as capreomycin (Capastat), rifampin (Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled);
antiviral medicines such as acyclovir (Zovirax), adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir);
cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid);
aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel).

This list is not complete and there may be other drugs that can interact with Asacol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Where can I get more information?
Your pharmacist can provide more information about Asacol.

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What does my medication look like?
Mesalamine is available with a prescription under the brand names Asacol, Lialda and Pentasa. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about Asacol, especially if it is new to you.

Asacol 400 mg Delayed-Release Tablets - reddish-brown, capsule-shaped tablets

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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 详细处方信息以本药内容附件PDF文件(201081722025922.pdf)的“原文Priscribing Information”为准
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更新日期: 2012-7-11
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