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  药店国别: 新西兰药房
产地国家: 新西兰
所属类别: 皮肤科药物->治疗痤疮药物
处方药:处方药
包装规格: 30克/支
计价单位:
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该药品相关信息网址1:
http://www.netdoctor.co.uk/medicines/100001381.html
原产地英文商品名:
ISOTREX GEL 0.05% 30 Grams
原产地英文药品名:
Isotretinoin GEL
中文参考商品译名:
爱索思0.05%凝胶 30克/支
中文参考药品译名:
异维A酸凝胶
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Comedon
英文适应病症2:
acne
临床试验期:
完成
中文适应病症参考翻译1:
粉刺
中文适应病症参考翻译2:
痤疮
药品信息:

Isotretinoin(第二代A酸)
商品名:爱索思凝胶isotrex Gel、爱索思乳膏isotrex Cream
顺式A酸(Isotrex)
它的结构及药理作用与第一代A酸all-trans Tretinoin相类似,差别在碳链接构上调整为13-顺式维他命A酸(13-cis-retinoic acid),降低了传统a酸的致畸胎作用,同时感旋光性、刺激性也下降。
A酸性皮肤炎的发生率,在第一代A酸为35%,爱索思则只有4%。但是0.05% Isotretinoin疗效也较为温和缓慢,与Tretinoin相同都是黄色药膏。

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Isotrex gelHow does it work?
Isotrex gel contains the active ingredient isotretinoin. It belongs to a group of medicines known as retinoids, which are derivatives of vitamin A.
It is not known exactly how isotretinoin works when applied to the skin, but it is thought to loosen the cells in the surface of the skin. This helps to unblock pores, so that the skins natural oil producing glands can function normally.
In addition, isotretinoin increases the turnover of the skin cells, which aids the natural exfoliation of the outer layers of skin. This also helps to unblock pores and decrease the formation of blackheads (comedones) and spots.
It may take six to eight weeks before definite beneficial effects on the skin can be seen.
What is it used for?
Mild to moderate acne
Warning!
• This preparation is for external use only.
• Avoid contact of this medicine with the eyes, mouth, mucous membranes (eg linings of the nose) and broken areas of skin or areas affected by eczema. Take care to avoid the gel building up in skin creases or the angles of the nose.
• If your skin is sunburnt you should not use this medicine until your skin is fully recovered, as it may potentially cause severe irritation to the skin.
• Avoid exposure to sunlight or sunlamps while using this medicine, as it increases the sensitivity of your skin. If exposure to sunlight cannot be avoided, use protective measures such as sun-creams or protective clothing.
• If you experience severe redness, peeling, or severe irritation of the skin you should apply this medicine less frequently or stop using it temporarily. If the irritation persists you should stop using the medicine completely and consult your doctor.
Use with caution in
• Eczema
• Personal or family history of cancer of the skin or lining of the internal body cavities (cutaneous epithelioma)
• Sensitive areas of skin such as the neck
Not to be used in
• Pregnancy
• Breastfeeding
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
• Isotretinoin taken by mouth during pregnancy can have serious adverse effects on a developing foetus. The safety of isotretinoin applied to the skin during pregnancy has not been established. This medicine should not be used by pregnant women. Seek medical advice from your doctor.
• There is no information available about the safety of this medicine during breastfeeding. For this reason, the manufacturer states that it should not be used during breastfeeding. Seek medical advice from your doctor.
Label warnings
• Follow the printed instructions you have been given with this medication.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
• Local skin reaction, eg stinging, burning, redness, irritation at site of application
• Increased sensitivity of skin to sunlight
• Skin peeling
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
The following should be used with caution while you are using Isotrex gel, as they may increase the likelihood of drying or irritating your skin:
• other topical medicines
• medicated or abrasive soaps and cleansers
• soaps and cosmetics with a strong drying effect
• products with high concentrations of alcohol, astringents, lime or spices
• preparations containing sulphur, resorcinol, benzoyl peroxide or salicylic acid.
Ask your pharmacist or doctor for further advice.

 

于2009-12-2更新

 

 

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