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  药店国别: 美国药房
产地国家: 美国
所属类别: 神经系统药物->帕金森症
处方药:处方药
包装规格: 0.5毫克/片 100片/盒
计价单位:
  点击放大  
生产厂家中文参考译名:
葛兰素史克
生产厂家英文名:
GlaxoSmithKline
该药品相关信息网址1:
http://www.requip.com/
该药品相关信息网址2:
http://www.requipxl.com/#ISI
原产地英文商品名:
REQUIP 0.5mg/tablet 100tablets/box
原产地英文药品名:
ROPINIROLE HYDROCHLORIDE
中文参考商品译名:
REQUIP 0.5毫克/片 100片/盒
中文参考药品译名:
盐酸罗匹尼罗
原产地国家批准上市年份:
1997/09/19
英文适应病症1:
RLS
英文适应病症2:
Parkinsonism
临床试验期:
完成
中文适应病症参考翻译1:
不宁腿综合症
中文适应病症参考翻译2:
帕金森氏症
药品信息:

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 详细处方信息以本药内容附件PDF文件(2009111121412313.pdf)的“原文Priscribing Information”为准
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药品简介
葛兰素史克公司(GSK)近日宣布,罗匹尼罗缓释片(ropinirole,Requip XL)用于治疗先天性帕金森病已在美国获得批准,本品由此成为首个一日1次口服治疗帕金森病的非麦角多巴胺激动剂。

帕金森病患者用药,当药物作用减弱时会出现症状复发的情况,III期临床研究结果显示在患者已使用的左旋多巴疗法基础上联用本品可减少患者症状不受控制的时间,研究中显示每天平均可减少2.1小时的症状不受控制时间。  
 
GSK公司表示,许多患者使用抗帕金森病药物时,每天需要多次服用,而在正确的时间服药对患者来说是个挑战,而且有的患者行动受限不方便自己服用。每天用药1次的Requip XL可使有效成分平稳释放,给患者带来方便。

Important information about Requip
Requip may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication. Talk with your doctor if you believe you have any intense or unusual urges while taking Requip.

Do not share this medication with another person, even if they have the same symptoms you do. Avoid drinking alcohol, which can increase some of the side effects of Requip. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by Requip. Tell your doctor if you regularly use any of these other medicines.

Requip may cause hallucinations (the sensation of hearing or seeing something that is not there), most commonly among elderly people. Call your doctor if you experience hallucinations.

Do not stop using Requip or change your dose without first talking to your doctor. You may have side effects such as fever, muscle stiffness, and confusion if you stop the medication suddenly or if you change doses.

Some people taking medicines for Parkinson's disease have developed skin cancer (melanoma). However, people with Parkinson's disease may have a higher risk than most people for developing melanoma. Talk to your doctor about your specific risk and what skin symptoms to watch for. You may need to have regular skin exams.

Before taking Requip
Requip may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert. You should not use Requip if you are allergic to ropinirole.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before you take this medication, tell your doctor if you are allergic to any drugs, or if you have:

heart disease;

high or low blood pressure;

mental illness or compulsive behaviors;

kidney disease;

liver disease; or

if you smoke.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking Requip. It is not known whether the medicine actually causes this effect. Talk with your doctor if you believe you have any intense or unusual urges while taking Requip.

FDA pregnancy category C. It is not known whether Requip is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ropinirole passes into breast milk or if it could harm a nursing baby.

Requip may reduce breast milk production. Do not take Requip without telling your doctor if you are breast-feeding a baby. Requip may cause hallucinations (the sensation of hearing or seeing something that is not there), most commonly among elderly people. Call your doctor if you experience hallucinations.

Some people taking medicines for Parkinson's disease have developed skin cancer (melanoma). However, people with Parkinson's disease may have a higher risk than most people for developing melanoma. Talk to your doctor about your specific risk and what skin symptoms to watch for. You may need to have regular skin exams.

How should I take Requip?
Take Requip exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

The dose and timing of Requip in treating Parkinson's disease is different from the dose and timing in treating RLS.

You may receive Requip in a starting kit that has each pill marked with the day you should take it. Do not mix these pills up because they each contain different amounts of Requip. The pills must be taken in order so that you gradually receive higher doses of the medication.

You may have a brief increase in side effects whenever your dose is changed.

Requip can be taken with or without food. Taking the medicine with food may help prevent nausea, which is a common side effect of Requip. It may take several weeks or months of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Do not stop taking Requip suddenly or change your doses, or you could have unpleasant withdrawal symptoms such as fever, muscle stiffness, and confusion. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Do not share this medication with another person, even if they have the same symptoms you do.

Store Requip at room temperature away from moisture and heat.

What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, weakness, fainting, agitation, confusion, hallucinations, muscle twitching, tingly feeling, and chest pain.

What should I avoid while taking Requip?
Requip can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid smoking, which can make Requip less effective. Avoid drinking alcohol. It can increase some of the side effects of Requip.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Requip side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;

fever, stiff muscles, confusion, sweating, fast or uneven heartbeats (especially if you stop taking Requip or use a lower dose);

hallucinations;

tremors (uncontrolled shaking); or

tight feeling in your chest, trouble breathing.

Call your doctor promptly if you fall asleep during a daily activity, if you faint, or if you have hallucinations (hearing or seeing something that is not there). Your doctor may want you to stop taking Requip, or take a lower dose.

Less serious Requip side effects may occur, such as:

mild nausea, vomiting, stomach pain, or loss of appetite;

worsened RLS symptoms early in the morning;

diarrhea or constipation;

dry mouth, sweating;

headache;

dizziness, drowsiness;

sleep problems (insomnia); or

agitation or anxiety.

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 详细处方信息以本药内容附件PDF文件(2009111121412313.pdf)的“原文Priscribing Information”为准
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更新日期: 2018-10-24
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